| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
U-73343 manufacturers
- U-73343
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- $38.00
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2026-07-17
- CAS:142878-12-4
- Purity: 99.06%
- Supply Ability: 10g
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| | U-73343 Basic information |
| Product Name: | U-73343 | | Synonyms: | U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;U-73343;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]- | | CAS: | 142878-12-4 | | MF: | C29H42N2O3 | | MW: | 466.66 | | EINECS: | | | Product Categories: | APIS | | Mol File: | 142878-12-4.mol |  |
| | U-73343 Chemical Properties |
| Boiling point | 641.5±55.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | +15C to +30C | | solubility | ethanol: 0.93 mg/mL | | form | powder | | pka | 10.68±0.40(Predicted) | | color | white | | Stability: | Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting. | | InChIKey | CJHWFIUASFBCKN-ZRJUGLEFSA-N | | SMILES | [H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OC)ccc24)NCCCCCCN5C(=O)CCC5=O |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | U-73343 Usage And Synthesis |
| Description | U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3Cell permeable. | | Uses | U-73343 is an inactive structural analog of U-73122. | | General Description | A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control. | | Biochem/physiol Actions | Cell permeable: yes | | storage | Store at RT | | References | [1] J E BLEASDALE. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.[J]. Journal of Pharmacology and Experimental Therapeutics, 1990, 255 2: 756-768.
[2] P MORLEY. A new, nongenomic estrogen action: the rapid release of intracellular calcium.[J]. Endocrinology, 1992, 131 3: 1305-1312. DOI:10.1210/endo.131.3.1505465
[3] Y MUTO T U T Nagao. The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell.[J]. Journal of Pharmacology and Experimental Therapeutics, 1997, 282 3: 1379-1388. |
| | U-73343 Preparation Products And Raw materials |
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