|
|
| | 1-(4-FLUOROBENZYL)PIPERAZINE Basic information |
| | 1-(4-FLUOROBENZYL)PIPERAZINE Chemical Properties |
| Melting point | 64 °C | | Boiling point | 112-114°C 2mm | | density | 1.103 | | refractive index | 1.5255-1.5275 | | Fp | 122℃ | | storage temp. | 2-8°C, protect from light | | pka | 9.13±0.10(Predicted) | | form | solid | | Appearance | Light yellow to yellow Solid | | InChI | 1S/C11H15FN2/c12-11-3-1-10(2-4-11)9-14-7-5-13-6-8-14/h1-4,13H,5-9H2 | | InChIKey | OOSZCNKVJAVHJI-UHFFFAOYSA-N | | SMILES | Fc1ccc(CN2CCNCC2)cc1 | | CAS DataBase Reference | 70931-28-1(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38-20/21/22 | | Safety Statements | 26-36-36/37/39 | | RIDADR | 3263 | | WGK Germany | 2 | | HazardClass | IRRITANT | | HS Code | 29335990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 1-(4-FLUOROBENZYL)PIPERAZINE Usage And Synthesis |
| Chemical Properties | clear yellow liquid after melting | | Uses | Precursor involved in the synthesis of a variety of biologically active molecules including:• ;Chemokine antagonists1• ;Pyrido[1,2-a]benzimidazoles with cytotoxic and antiplasmodial activity2• ;Pyrimidine derivatives as cholinesterase and Aβ-aggregation inhibitors3• ;Chlorokojic acid derivatives with antibacterial and antiviral activities4• ;EGFR and Aurora A kinase inhibitors5• ;Neurokinin-2 receptor antagonists6 | | Uses | Precursor involved in the synthesis of a variety of biologically active molecules including:
- Chemokine antagonists
- Pyrido[1,2-a]benzimidazoles with cytotoxic and antiplasmodial activity
- Pyrimidine derivatives as cholinesterase and Aβ-aggregation inhibitors
- Chlorokojic acid derivatives with antibacterial and antiviral activities
- EGFR and Aurora A kinase inhibitors
- Neurokinin-2 receptor antagonists
|
| | 1-(4-FLUOROBENZYL)PIPERAZINE Preparation Products And Raw materials |
|