3-(2,2,2-trifluoroacetamido)propanoyl chloride manufacturers
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| | 3-(2,2,2-trifluoroacetamido)propanoyl chloride Basic information |
| | 3-(2,2,2-trifluoroacetamido)propanoyl chloride Chemical Properties |
| Boiling point | 101-102 °C(Press: 6 Torr) | | density | 1.434±0.06 g/cm3(Predicted) | | pka | 10.58±0.46(Predicted) |
| | 3-(2,2,2-trifluoroacetamido)propanoyl chloride Usage And Synthesis |
| Uses | N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | Biological Activity | 3-(2,2,2-trifluoroacetamido)propanoyl chloride is a cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs). | | in vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | | target | | | IC 50 | Cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | 3-(2,2,2-trifluoroacetamido)propanoyl chloride Preparation Products And Raw materials |
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