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| | 8-Methylquinoline Basic information |
| | 8-Methylquinoline Chemical Properties |
| Melting point | -80 °C | | Boiling point | 245 °C | | density | 1.052 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.614(lit.) | | Fp | 221 °F | | storage temp. | Room Temperature | | solubility | Chloroform, Methanol | | pka | 5.03±0.17(Predicted) | | form | Liquid | | color | Clear yellow | | Specific Gravity | 1.052 | | Water Solubility | 0.1-0.5 g/100 mL at 17 ºC | | BRN | 111340 | | InChIKey | JRLTTZUODKEYDH-UHFFFAOYSA-N | | CAS DataBase Reference | 611-32-5(CAS DataBase Reference) | | NIST Chemistry Reference | Quinoline, 8-methyl-(611-32-5) | | EPA Substance Registry System | 8-Methylquinoline (611-32-5) |
| | 8-Methylquinoline Usage And Synthesis |
| Chemical Properties | clear yellow liquid | | Uses | 8-Methylquinoline has been used in preparation of osmium chloridophosphine complexes, as quinoline carbene tautomers.Tumorigenic potential of 8-methylquinoline has been evaluated in newborn CD-1 mice and Sprague-Dawley rats. | | Uses | 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines. | | Definition | ChEBI: A methylquinoline carrying a methyl substituent at position 8. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 45, p. 1514, 1980 DOI: 10.1021/jo01296a035 | | General Description | Yellow liquid or oil. | | Air & Water Reactions | Slightly soluble in water. | | Reactivity Profile | 8-Methylquinoline may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. | | Fire Hazard | 8-Methylquinoline is combustible. | | Purification Methods | Purify it as for 2-methylquinoline. The phosphate and picrate have m 158o and m 201o, respectively. [Beilstein 20 III/IV 3500, 20/7 V 405.] |
| | 8-Methylquinoline Preparation Products And Raw materials |
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