2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol

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2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol Basic information
Product Name:2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol
Synonyms:2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol;1-Naphthalenol, 2-[5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl]-;WAY-297629;VEGFR-2-IN-65
CAS:371213-22-8
MF:C21H18N2O3
MW:346.38
EINECS:
Product Categories:
Mol File:371213-22-8.mol
2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol Structure
2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol Chemical Properties
Boiling point 575.1±50.0 °C(Predicted)
density 1.272±0.06 g/cm3(Predicted)
pka8.48±0.50(Predicted)
Safety Information
MSDS Information
2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol Usage And Synthesis
UsesVEGFR-2-IN-65 (Compound 07) is a VEGFR-2 inhibitor. VEGFR-2-IN-65 has H-bond interactions with Cys180. VEGFR-2-IN-65 inhibits tube formation in HUVECs[1].
IC 50VEGFR2
References[1] Zhang L, et al. Discovery of novel vascular endothelial growth factor receptor 2 inhibitors: a virtual screening approach. Chem Biol Drug Des. 2012 Dec;80(6):893-901. DOI:10.1111/cbdd.12036
2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol Preparation Products And Raw materials
Tag:2-(5-(3,4-dimethoxyphenyl)-1H-pyrazol-3-yl)naphthalen-1-ol(371213-22-8) Related Product Information
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