廿二碳四烯酸
| 中文名称 | 廿二碳四烯酸 |
|---|---|
| 中文同义词 | 7,10,13,16-二十二碳四烯酸;廿二碳四烯酸;廿二碳四烯酸 10MG;肾上腺酸(溶解于乙醇);二十二碳四烯酸(顺-7,10,13,16);顺式-7,10,13,16-二十二碳四烯酸;二十二碳四烯酸;肾上腺酸(乙醇溶液) |
| 英文名称 | ADRENIC ACID |
| 英文同义词 | CIS-7,10,13,16,19-DOCOSA-TETRAENOIC ACID;CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID;DOCOSATETRAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID;cis-7,10,13,16-Docosatetraenoic acid, C22:4n6;7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID;ADRENIC ACID |
| CAS号 | 28874-58-0 |
| 分子式 | C22H36O2 |
| 分子量 | 332.52 |
| EINECS号 | |
| 相关类别 | 脂肪酸;生化试剂;Unsaturated fatty acids and derivatives;DJ - DZUnsaturated fatty acids and derivatives;Alphabetic;Omega 6 fatty acids and derivatives;Polyunsaturated;D |
| Mol文件 | 28874-58-0.mol |
| 结构式 |  |
廿二碳四烯酸 性质
| 沸点 | 161-164.5 °C(Press: 0.07 Torr) |
|---|---|
| 密度 | 0.9220 g/cm3 |
| 储存条件 | −20°C |
| 溶解度 | 氯仿（微溶）、甲醇（微溶） |
| 酸度系数(pKa) | 4.76±0.10(Predicted) |
| 形态 | 油状 |
| 颜色 | 无色 |
| 稳定性 | 感光 |
| InChIKey | TWSWSIQAPQLDBP-DOFZRALJSA-N |
| SMILES | C(O)(=O)CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC |
|
Human Endogenous Metabolite
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Adrenic acid is produced via the elongation of arachidonic acid by ELOVL2 and 5. Interestingly, the hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). It is also found that the concentrations of phospholipid species containing Adrenic Acid, such as PC or PE (40:4) (containing side chain 18:0/22:4), and LPC 22:4 (sn-1/sn-2), are also significantly increased. (sn-1/sn-2). The hepatic and plasma levels of Adrenic Acid, which is an omega 6 polyunsaturated fatty acid (PUFA), exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid.
安全信息
| WGK Germany | 3 |
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| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-W013215 | 廿二碳四烯酸 Adrenic Acid | 28874-58-0 | 5 mg (300 mM * 50 μL in Ethanol) | 600元 |
| 2025/12/22 | HY-W013215 | 廿二碳四烯酸 Adrenic Acid | 28874-58-0 | 10mg(300mM * 100μL in Ethanol) | 900元 |