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| | 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Basic information |
| | 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Chemical Properties |
| Melting point | 34-40℃ | | Boiling point | 295.4±33.0 °C(Predicted) | | density | 1.114±0.06 g/cm3(Predicted) | | Fp | >110℃ | | storage temp. | 2-8°C | | solubility | Soluble in methanol. | | form | Oil | | pka | -2.13±0.40(Predicted) | | color | Clear Yellow | | Sensitive | Air Sensitive | | InChI | InChI=1S/C11H19NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h8-9H,4-7H2,1-3H3 | | InChIKey | JYUQEWCJWDGCRX-UHFFFAOYSA-N | | SMILES | N1(C(OC(C)(C)C)=O)CCC(C=O)CC1 | | CAS DataBase Reference | 137076-22-3(CAS DataBase Reference) |
| Hazard Codes | Xi,N,Xn | | Risk Statements | 36/37/38-50-22 | | Safety Statements | 26-36/37/39-61 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | WGK 3 | | HS Code | 29333990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Usage And Synthesis |
| Chemical Properties | Clear Yellow Oil | | Uses | Reactant for synthesis of:• ;Pim-1 inhibitors1• ;Selective GPR119 agonists for type II diabetes2• ;M-tropic (R5) HIV-1 replication inhibitors3• ;HDAC inhibitors4• ;Selective 5-HT6 antagonists5Reactant for three-component vinylogous Mannich reactions6 | | Uses | 1-Boc-piperidine-4-carboxaldehyde is used as reactant for synthesis of Pim-1 inhibitors, selective GPR119 agonists for type II diabetes, M-tropic (R5) HIV-1 replication inhibitors, HDAC inhibitors and selective 5-HT6 antagonists. It is also used as reactant for three-component vinylogous Mannich reactions | | Uses | An intermediate for polycyclic indazole derivatives that are ERK inhibitors. |
| | 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Preparation Products And Raw materials |
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