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| | (11(12)-DiHET-d11 Basic information |
| Product Name: | (11(12)-DiHET-d11 | | Synonyms: | (11(12)-DiHET-d11;(±)11(12)-DiHET-d11 | | CAS: | | | MF: | C20H23D11O4 | | MW: | 349.549339558 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | (11(12)-DiHET-d11 Chemical Properties |
| solubility | DMF: 50 mg/ml DMSO: 50 mg/ml Ethanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml |
| | (11(12)-DiHET-d11 Usage And Synthesis |
| Description | (±)11(12)-DiHET-d11 is intended for use as an internal standard for the quantification of 11(12)-DiHET by GC- or LC-MS. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formed via enzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.1,2,3WARNING This product is not for human or veterinary use. | | References | [1] X FANG. Functional implications of a newly characterized pathway of 11,12-epoxyeicosatrienoic acid metabolism in arterial smooth muscle.[J]. Circulation research, 1996, 79 4: 784-793. DOI: 10.1161/01.res.79.4.784 [2] D C ZELDIN. Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase.[J]. The Journal of Biological Chemistry, 1993, 268 9: 6402-6407.
[3] GUODONG ZHANG Bruce D H Sean Kodani. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer[J]. Progress in lipid research, 2014, 53: Pages 108-123. DOI: 10.1016/j.plipres.2013.11.003 |
| | (11(12)-DiHET-d11 Preparation Products And Raw materials |
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