Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 manufacturers
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| | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Basic information |
| Product Name: | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 | | Synonyms: | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2;L-Alaninamide, 1-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-S-[(4-methoxyphenyl)methyl]-L-cysteinyl-L-tryptophyl-L-alanyl-L-arginyl-3-[(2,4-dinitrophenyl)amino]-;1-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-S-[(4-methoxyphenyl)methyl]-L-cysteinyl-L-tryptophyl-L-alanyl-L-arginyl-3-[(2,4-dinitrophenyl)amino]-L-alaninamide;Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap (Dnp)-NH2 trifluoroacetate salt | | CAS: | 1926163-82-7 | | MF: | C66H82N16O17S | | MW: | 1403.52 | | EINECS: | | | Product Categories: | | | Mol File: | 1926163-82-7.mol |  |
| | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Chemical Properties |
| density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Formic Acid: 1 mg/ml | | form | A lyophilized powder | | pka | 12.98±0.46(Predicted) | | color | White to off-white |
| | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Usage And Synthesis |
| Description | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).1 Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively. | | Uses | Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). | | IC 50 | MMP-14 | | References | 1. Eckhouse, S.R., Akerman, A.W., Logdon, C.B., et al. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: Relationship to interstitial microRNA dynamics and myocardial function J. Thorac. Cardiovasc. Surg. 145(1),267-275(2013). |
| | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 Preparation Products And Raw materials |
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