PHGDH-inactive
| 中文名称 | PHGDH-inactive |
|---|---|
| 中文同义词 | 化合物PHGDH-INACTIVE;N-(4,6-二甲基吡啶-2-基)-4-(吡啶-4-基)哌嗪-1-硫代甲酰胺;化合物PHGDH-INACTIVE,10 MM DMSO 溶液;【进口原装】NCT-503 Inactive Control/1914971-16-6;【进口分装现货】NCT-503 Inactive Control/1914971-16-6;【进口原装】NCT-503 Inactive Control/1914971-16-6;【进口分装现货】NCT-503 Inactive Control/1914971-16-6 |
| 英文名称 | PHGDH-inactive |
| 英文同义词 | PHGDH-inactive;N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)-1-piperazinecarbothioamide;1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)-;NCT-503 Inactive Control >=98% (HPLC);NCT-502,PHGDH-inactive,Inhibitor,control,PHGDH,PHGDH inactive,negative,PHGDHinactive,inhibit,activity;N-(4,6-Dimethylpyridin-2-yl)-4-(pyridin-4-yl)piperazine-1-carbothioamide;PHGDH-inactive, 10 mM in DMSO;NCT-503 Inactive Control |
| CAS号 | 1914971-16-6 |
| 分子式 | C17H21N5S |
| 分子量 | 327.45 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1914971-16-6.mol |
| 结构式 |  |
PHGDH-inactive 性质
| 沸点 | 497.9±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.268±0.06 g/cm3(Predicted) |
| 储存条件 | 4°C, protect from light |
| 溶解度 | DMF：2 mg/ml；二甲基亚砜：5 mg/ml； DMSO:PBS (pH 7.2)(1:5)：0.16 mg/ml |
| 形态 | 结晶固体 |
| 酸度系数(pKa) | 12.96±0.20(Predicted) |
| 颜色 | white to beige |
| InChI | 1S/C17H21N5S/c1-13-11-14(2)19-16(12-13)20-17(23)22-9-7-21(8-10-22)15-3-5-18-6-4-15/h3-6,11-12H,7-10H2,1-2H3,(H,19,20,23) |
| InChIKey | ITLPIAAGIQAGRA-UHFFFAOYSA-N |
| SMILES | CC1=CC(NC(N2CCN(C3=CC=NC=C3)CC2)=S)=NC(C)=C1 |
PHGDH-inactive 对 PHGDH 无活性(IC50>57 μM)，可作为 NCT-502 和 NCT-503 的阴性对照。
安全信息
| WGK Germany | WGK 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 经皮刺激 类别2 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-121733 | PHGDH-inactive | 1914971-16-6 | 1 mg | 224元 |
| 2025/12/22 | HY-121733 | PHGDH-inactive PHGDH-inactive | 1914971-16-6 | 10 mM * 1 mLin DMSO | 395元 |