| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:MFN2 agonist-1
CAS:2230047-87-5
Purity:98% Package:5mg Remarks:S35524
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:MFN2 agonist-1
CAS:2230047-87-5
Package:5mg/RMB 7000;100mg/RMB 17500;50mg/RMB 12900
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:MFN2 agonist-1
CAS:2230047-87-5
|
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| | MFN2 agonist B-A l Basic information |
| Product Name: | MFN2 agonist B-A l | | Synonyms: | MFN2 agonist B-A l;Urea, N-[2-[(5-cyclopropyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio]ethyl]-N'-(2-methylcyclohexyl)-;MFN2 agonist-1 | | CAS: | 2230047-87-5 | | MF: | C21H29N5OS | | MW: | 399.55 | | EINECS: | | | Product Categories: | | | Mol File: | 2230047-87-5.mol |  |
| | MFN2 agonist B-A l Chemical Properties |
| density | 1.34±0.1 g/cm3(Predicted) | | pka | 13.53±0.46(Predicted) | | form | Solid | | color | White to off-white |
| | MFN2 agonist B-A l Usage And Synthesis |
| Uses | MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial “clumping” (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M. | | References | [1] Rocha AG, et al. MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A. Science. 2018 Apr 20;360(6386):336-341. DOI:10.1126/science.aao1785 |
| | MFN2 agonist B-A l Preparation Products And Raw materials |
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