Caspase-8 antibody

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Company Name: Fedprotein  
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Caspase-8 antibody Basic information
Source Reactivity Background References
Product Name:Caspase-8 antibody
Synonyms:Caspase-8 antibody
CAS:
MF:
MW:0
EINECS:
Product Categories:Regulation of Apoptosis
Mol File:Mol File
Caspase-8 antibody Structure
Caspase-8 antibody Chemical Properties
Safety Information
MSDS Information
Caspase-8 antibody Usage And Synthesis
SourceRabbit
ReactivityMouse
BackgroundApoptosis induced through the CD95 receptor and tumor necrosis factor receptor 1 activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10. Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage.
References[1] Muzio, M. et al. (1996) Cell 85, 817-27.
[2] Boldin, M.P. et al. (1996) Cell 85, 803-15.
[3] Fernandes-Alnemri, T. et al. (1996) Proc Natl Acad Sci U S A 93, 7464-9.
Caspase-8 antibody Preparation Products And Raw materials
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