Bacterial Sortase Substrate III, Abz/DNP

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Bacterial Sortase Substrate III, Abz/DNP Basic information
Product Name:Bacterial Sortase Substrate III, Abz/DNP
Synonyms:Bacterial Sortase Substrate III, Abz/DNP
CAS:2857862-12-3
MF:
MW:0
EINECS:
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Mol File:Mol File
Bacterial Sortase Substrate III, Abz/DNP Structure
Bacterial Sortase Substrate III, Abz/DNP Chemical Properties
Sequence{Abz}-Leu-Pro-Glu-Thr-Gly-{Lys(Dnp)}-NH2
Safety Information
MSDS Information
Bacterial Sortase Substrate III, Abz/DNP Usage And Synthesis
UsesBacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.
References[1] Zhang J, et al. Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22. DOI:10.1073/pnas.1408601111
Bacterial Sortase Substrate III, Abz/DNP Preparation Products And Raw materials
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