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| Product Name: | BA 1 | | Synonyms: | L-Norleucinamide, D-tyrosyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-β-alanyl-L-histidyl-L-phenylalanyl- | | CAS: | 183241-31-8 | | MF: | C57H76N14O11 | | MW: | 1133.32 | | EINECS: | | | Product Categories: | | | Mol File: | 183241-31-8.mol |  |
| Boiling point | 1636.8±65.0 °C(Predicted) | | density | 1.300±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.97±0.15(Predicted) | | Sequence | {d-Tyr}-Gln-Trp-Ala-Val-{Bal}-His-Phe-{Nle}-NH2 |
| Uses | BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1]. | | References | [1] Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61. DOI:10.1016/j.peptides.2014.12.005 |
| | BA 1 Preparation Products And Raw materials |
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