PROTAC Linker 2

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Company Name: TargetMol Chemicals Inc.  
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Company Name: Shanghai hongqu biomedical technology co. LTD  
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PROTAC Linker 2 Basic information
Product Name:PROTAC Linker 2
Synonyms:PROTAC Linker 2;Hexanoic acid, 6-[[5-[(6-chlorohexyl)oxy]pentyl]oxy]-, 1,1-dimethylethyl ester;tert-Butyl 6-((5-((6-chlorohexyl)oxy)pentyl)oxy)hexanoate
CAS:1835705-52-6
MF:C21H41ClO4
MW:393
EINECS:
Product Categories:
Mol File:1835705-52-6.mol
PROTAC Linker 2 Structure
PROTAC Linker 2 Chemical Properties
Boiling point 456.8±40.0 °C(Predicted)
density 0.975±0.06 g/cm3(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
PROTAC Linker 2 Usage And Synthesis
UsesBoc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.
IC 50Alkyl/ether
References[1] Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10. DOI:10.1002/anie.201507634
[2] ARYL SULFONOHYDRAZIDES. US 20170121321 A1.
PROTAC Linker 2 Preparation Products And Raw materials
Tag:PROTAC Linker 2(1835705-52-6) Related Product Information
Hexanoic acid, 6-[[5-[(6-chlorohexyl)oxy]pentyl]oxy]- PROTAC Linker 1 Propanoic acid, 3-[3-(3-chloropropoxy)propoxy]-, 1,1-dimethylethyl ester Eicosanedioic acid, 1,20-bis(1,1-dimethylethyl) ester Hexanedioic acid, 1-(1,1-dimethylethyl) 6-ethyl ester Pentanoic acid, 5-chloro-, 1,1-dimethylethyl ester