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5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine manufacturers
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| | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine Basic information |
| Product Name: | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine | | Synonyms: | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine;Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-5-methyl- (9CI);2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine;2’-beta-C-Methyl-6-thioinosine;(1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-yl)-carbamicacid9H-fluoren-9-ylmethylester | | CAS: | 176755-86-5 | | MF: | C46H43N3O8 | | MW: | 765.85 | | EINECS: | | | Product Categories: | | | Mol File: | 176755-86-5.mol | ![5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine Structure](CAS/20200611/GIF/176755-86-5.gif) |
| | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine Chemical Properties |
| density | 1.298±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 6.394±0.40(predicted) |
| | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine Usage And Synthesis |
| Uses | 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. | | References | [1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308 |
| | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-N4-[(9H-fluoren-9-ylmethoxy) carbonyl]-5-methylcytidine Preparation Products And Raw materials |
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