| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:CCI-006
CAS:292053-42-0
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
CCI 006) manufacturers
- CCI-006
-
- $48.00 / 1mg
-
2025-05-02
- CAS:292053-42-0
- Min. Order:
- Purity: 96.04%
- Supply Ability: 10g
- CCI-006
-
- $48.00 / 1mg
-
2025-04-30
- CAS:292053-42-0
- Min. Order:
- Purity: 96.04%
- Supply Ability: 10g
|
| | CCI 006) Basic information |
| Product Name: | CCI 006) | | Synonyms: | CCI 006);CCI-006
(CCI006;2-Propenoic acid, 3-[5-[4-(aminosulfonyl)phenyl]-2-furanyl]-2-cyano-, methyl ester;Methyl 2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate;CCI-006,Inhibitor,CCI006,inhibit,Mitochondrial Metabolism,CCI 006;CCI-006, 10 mM in DMSO;METHYL 3-(5-(4-(AMINOSULFONYL)PHENYL)-2-FURYL)-2-CYANOACRYLATE | | CAS: | 292053-42-0 | | MF: | C15H12N2O5S | | MW: | 332.33 | | EINECS: | | | Product Categories: | | | Mol File: | 292053-42-0.mol |  |
| | CCI 006) Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO : ≥ 83.33 mg/mL (250.74 mM) | | form | Solid | | color | Light yellow to yellow |
| | CCI 006) Usage And Synthesis |
| Uses | CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1]. | | References | [1] Somers K, et al. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene. 2019 Jan 22. DOI:10.1038/s41388-018-0666-5 |
| | CCI 006) Preparation Products And Raw materials |
|