4,4'-Oxybis[benzamide]

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4,4'-Oxybis[benzamide] manufacturers

  • OUL35
  • OUL35 pictures
  • $31.00
  • 2026-07-27
  • CAS:6336-34-1
  • Purity: 99.30%
  • Supply Ability: 10g
4,4'-Oxybis[benzamide] Basic information
Product Name:4,4'-Oxybis[benzamide]
Synonyms:4,4'-Oxybis[benzamide];NSC39047;Benzamide, 4,4'-oxybis-;OUL35 >=98% (HPLC);ARTD10,PARP,inhibit,DNA,OUL 35,NSC 39047,apoptosis,NSC-39047,PARP10,poly ADP ribose polymerase,damage,HeLa,OUL35,Inhibitor,OUL-35;4,4'-Oxydibenzamide , OUL35;4-(4-carbamoylphenoxy)benzamide;OUL35, 10 mM in DMSO
CAS:6336-34-1
MF:C14H12N2O3
MW:256.26
EINECS:
Product Categories:
Mol File:6336-34-1.mol
4,4'-Oxybis[benzamide] Structure
4,4'-Oxybis[benzamide] Chemical Properties
Boiling point 488.8±30.0 °C(Predicted)
density 1.298±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMF: 5 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml
form A crystalline solid
pka15.76±0.50(Predicted)
color White to off-white
InChI1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18)
InChIKeyXZRCQWLPMXFGHE-UHFFFAOYSA-N
SMILESO=C(N)C1=CC=C(OC2=CC=C(C(N)=O)C=C2)C=C1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
4,4'-Oxybis[benzamide] Usage And Synthesis
UsesOUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM[1].
Biological ActivityOUL35 is a cell penetrant, potent and selective ARTD10/PARP10 inhibitor. OUL35 rescues HeLa cells from ARTD10 induced apoptotic cell death.
IC 50ARTD10/PARP10: 329 nM (IC50)
storageStore at +4°C
References[1] Harikanth Venkannagari, et al. Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage. Cell Chem Biol. 2016 Oct 20;23(10):1251-1260. DOI:10.1016/j.chembiol.2016.08.012
4,4'-Oxybis[benzamide] Preparation Products And Raw materials
Raw materials4,4'-Dicarboxydiphenyl Ether
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