3-[(2-Aminoethyl)dithio]propionic acid

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3-[(2-Aminoethyl)dithio]propionic acid Basic information
Product Name:3-[(2-Aminoethyl)dithio]propionic acid
Synonyms:Aminoethyl-SS-propionic acid;Propanoic acid, 3-[(2-aminoethyl)dithio]-;3-((2-aminoethyl)disulfanyl)propanoic acid;3-[(2-Aminoethyl)dithio]propanoic acid
CAS:15579-00-7
MF:C5H11NO2S2
MW:181.28
EINECS:
Product Categories:Nitric Oxide Reagents;Cross Linking Reagents;Amines;Sulfur & Selenium Compounds
Mol File:15579-00-7.mol
3-[(2-Aminoethyl)dithio]propionic acid Structure
3-[(2-Aminoethyl)dithio]propionic acid Chemical Properties
Melting point 138-141oC
Boiling point 339.5±27.0 °C(Predicted)
density 1.320±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Soluble in Water, DMSO
form A solid
pka4.20±0.10(Predicted)
color White to off-white
Stability:Hygroscopic
InChIInChI=1S/C5H11NO2S2/c6-2-4-10-9-3-1-5(7)8/h1-4,6H2,(H,7,8)
InChIKeyHMMFDEBVQNRZLJ-UHFFFAOYSA-N
SMILESC(O)(=O)CCSSCCN
Safety Information
MSDS Information
3-[(2-Aminoethyl)dithio]propionic acid Usage And Synthesis
DescriptionAminoethyl-SS-propionic acid is a cleavable compound containing a terminal amine and carboxylic acid group. The disulfide bonds can be cleaved using Dithiothreitol (DTT) reagent. The terminal amine can be reacted with carboxylic acid, activated NHS esters and other carbonyl compounds. The terminal carboxylic acid can be reacted with primary amines in the presence of activators such as EDC and HATU to form a stable amide bond.
Chemical Properties3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is White Solid
Uses3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is a useful reversible immobilization or crossliking reagent
IC 50Disulfide Cleavable Linker; Cleavable Linker
3-[(2-Aminoethyl)dithio]propionic acid Preparation Products And Raw materials
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