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| | (E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene Basic information |
| Product Name: | (E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene | | Synonyms: | TRANS-1-METHOXY-2-METHYL-3-(TRIMETHYLSI&;(1e,3z)-1-methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene;(1e,3z)-1-methoxy-2-methyl-3-[(trimethylsilyl)oxy]-penta-1,3-diene;[(1-(2-Methoxy-1-methylvinyl)propenyloxy]trimethylsilan, (1E,3Z)-1-Methoxy-2-methyl-3-[(trimethylsilyl)oxy]-penta-1,3-diene;[(1-(2-Methoxy-1-methylvinyl)propenyloxy]trimethylsilan;1-Methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene;(1E 3Z)-1-METHOXY-2-METHYL-3-(TRIMETHYL&;Silane, [[(1Z)-1-[(1E)-2-methoxy-1-methylethenyl]-1-propen-1-yl]oxy]trimethyl- | | CAS: | 72486-93-2 | | MF: | C10H20O2Si | | MW: | 200.35 | | EINECS: | | | Product Categories: | Building Blocks;Chemical Synthesis;Enol Ethers;Organic Building Blocks;Oxygen Compounds | | Mol File: | 72486-93-2.mol |  |
| | (E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene Chemical Properties |
| Boiling point | 65 °C/6 mmHg (lit.) | | density | 0.899 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.4650(lit.) | | Fp | 178 °F | | storage temp. | 2-8°C | | InChI | 1S/C10H20O2Si/c1-7-10(9(2)8-11-3)12-13(4,5)6/h7-8H,1-6H3/b9-8+,10-7- | | InChIKey | SSGAQVOLXCOJGN-AZRUORMVSA-N | | SMILES | CO\C=C(C)\C(O[Si](C)(C)C)=C\C |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Oral |
| | (E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene Usage And Synthesis |
| Uses | (1E,3Z)-1-Methoxy-2-methyl-3-(trimethylsilyloxy)-1,3-pentadiene used as a reactant for:Preparation of migrastatin analog as cell migration inhibitor for treatment of tumor metastasis2Preparation of dihydropyridinones by chlorosilane-promoted aza-Diels-Alder addition3Synthesis on non-proteinogenic amino esters via stereoselective Lewis acid-catalyzed aza-Diels-Alder cycloaddition with conjugated (cyclo)dienes4 | | Uses | Danishefsky diene used as a reactant for:
Preparation of migrastatin analog as cell migration inhibitor for treatment of tumor metastasis
Preparation of dihydropyridinones by chlorosilane-promoted aza-Diels-Alder addition
Synthesis on non-proteinogenic amino esters via stereoselective Lewis acid-catalyzed aza-Diels-Alder cycloaddition with conjugated (cyclo)dienes | | Synthesis | (1E,3Z)-1-Methoxy-2-Methyl-3-(triMethylsilyloxy)-1,3-pentadiene is prepared in multigram quantities as a colorless or slightly yellow liquid from 3- pentanone and ethyl formate via a three-step procedure (ca. 40% overall yield). |
| | (E,Z)-1-Methoxy-2-methyl-3- (trimethylsilyloxy)-1,3-pentadiene Preparation Products And Raw materials |
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