SNIPER(ABL)-058

SNIPER(ABL)-058 Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:SNIPER(ABL)-058 CAS:2222354-61-0 Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel:	028-81700200 18116577057
Email:	3003855609@qq.com
Products Intro:	Product Name:SNIPER(ABL)-058 CAS:2222354-61-0 Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg；500mg；1g

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:SNIPER(ABL)-058 CAS:2222354-61-0 Package:100mg;500mg

Company Name:	Biosynth Biological Technology (Suzhou) Co Ltd
Tel:	51288865780
Email:	sales@biosynth.com
Products Intro:	Product Name:SNIPER(ABL)-058 CAS:2222354-61-0

SNIPER(ABL)-058 Basic information

Product Name:	SNIPER(ABL)-058
Synonyms:	SNIPER(ABL)-058;Benzamide, 1-[[4-[2-[2-[2-[2-[3-[[2-[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)-1-oxopropyl]amino]acetyl]-2-pyrrolidinyl]-4-thiazolyl]carbonyl]phenoxy]ethoxy]ethoxy]ethoxy]acetyl]-1-piperazinyl]methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-
CAS:	2222354-61-0
MF:	C62H75N11O9S
MW:	1150.41
EINECS:
Product Categories:
Mol File:	2222354-61-0.mol

SNIPER(ABL)-058 Chemical Properties

density	1.279±0.06 g/cm3(Predicted)
pka	13.28±0.70(Predicted)

Safety Information

MSDS Information

SNIPER(ABL)-058 Usage And Synthesis

Uses	SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].
References	[1] Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666. DOI:10.1111/cas.13284

SNIPER(ABL)-058 Preparation Products And Raw materials

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