| Company Name: |
Wuhan Topule |
| Tel: |
+86-02787215551 19945035818 |
| Email: |
2936752263@qq.com |
|
| | Bay 43-9006 (D4) Basic information |
| | Bay 43-9006 (D4) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | Bay 43-9006 (D4) Usage And Synthesis |
| Description | Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
| | Uses | Sorafenib-d4 is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively. | | References | [1]. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109. |
| | Bay 43-9006 (D4) Preparation Products And Raw materials |
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