| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Complement C5-IN-1
CAS:2365402-67-9
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Complement C5-IN-1 manufacturers
- Complement C5-IN-1
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- $93.00 / 1mg
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2026-01-30
- CAS:2365402-67-9
- Min. Order:
- Purity: 99.20%
- Supply Ability: 10g
- Complement C5-IN-1
-
- $93.00 / 1mg
-
2026-01-30
- CAS:2365402-67-9
- Min. Order:
- Purity: 99.20%
- Supply Ability: 10g
|
| | Complement C5-IN-1 Basic information |
| Product Name: | Complement C5-IN-1 | | Synonyms: | COMPOUND C5-IN-1 (COMPOUND 7);Complement C5-IN-1;C5 complement inhibitor 7;Complement C-5-IN-1,Complement C5 IN 1,Complement C5IN1;Benzoic acid, 5-methoxy-2-[[[[(1S)-1-(2-methoxyphenyl)ethyl]amino]carbonyl]amino]-4-[(4-methylpentyl)oxy]-;Complement C5-IN-1, 10 mM in DMSO | | CAS: | 2365402-67-9 | | MF: | C24H32N2O6 | | MW: | 444.52 | | EINECS: | | | Product Categories: | | | Mol File: | 2365402-67-9.mol |  |
| | Complement C5-IN-1 Chemical Properties |
| Boiling point | 576.9±50.0 °C(Predicted) | | density | 1.179±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: ≥ 100 mg/mL (224.96 mM) | | form | Solid | | pka | 3.92±0.36(Predicted) | | color | White to off-white |
| | Complement C5-IN-1 Usage And Synthesis |
| Description | Complement C5-IN-1 is the first potent inhibitor of C5 complement protein. | | Uses | Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77μM[1]. | | References | [1] Jendza K, et al. A small-molecule inhibitor of C5 complement protein. Nat Chem Biol. 2019 Jul;15(7):666-668. DOI:10.1038/s41589-019-0303-9 |
| | Complement C5-IN-1 Preparation Products And Raw materials |
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