MC-Sq-Cit-PAB-Gefitinib

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MC-Sq-Cit-PAB-Gefitinib Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:MC-Sq-Cit-PAB-Gefitinib
CAS:1941168-63-3
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:MC-Sq-Cit-PAB-Gefitinib
CAS:1941168-63-3
Purity:97.0% Package:5mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:MC-Sq-Cit-PAB-Gefitinib
CAS:1941168-63-3
Package:100mg;500mg
Company Name: Adooq Bioscience LLC  
Tel: 400-025-6535
Email: sales@adooq.cn
Products Intro: Product Name:MC-Sq-Cit-PAB-Gefitinib
CAS:1941168-63-3
MC-Sq-Cit-PAB-Gefitinib Basic information
Product Name:MC-Sq-Cit-PAB-Gefitinib
Synonyms:MC-Sq-Cit-PAB-Gefitinib
CAS:1941168-63-3
MF:C50H61ClFN10O9+
MW:1000.55
EINECS:
Product Categories:
Mol File:1941168-63-3.mol
MC-Sq-Cit-PAB-Gefitinib Structure
MC-Sq-Cit-PAB-Gefitinib Chemical Properties
Safety Information
MSDS Information
MC-Sq-Cit-PAB-Gefitinib Usage And Synthesis
UsesMC-Sq-Cit-PAB-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
IC 50Traditional Cytotoxic Agents
References[1] FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.
[2] Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119. DOI:10.1038/nchem.2635
MC-Sq-Cit-PAB-Gefitinib Preparation Products And Raw materials
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