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| | Mal-VC-PAB-DM1 Basic information |
| Product Name: | Mal-VC-PAB-DM1 | | Synonyms: | Mal-VC-PAB-DM1;Maytansine, N2'-deacetyl-N2'-[[[4-[[N-[6-(1,5-dihydro-1,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]- | | CAS: | 1464051-44-2 | | MF: | C61H82ClN9O17 | | MW: | 1248.81 | | EINECS: | | | Product Categories: | | | Mol File: | 1464051-44-2.mol |  |
| | Mal-VC-PAB-DM1 Chemical Properties |
| Boiling point | 1343.1±65.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | solubility | DMSO : 75 mg/mL (60.06 mM; Need ultrasonic) | | pka | 9.82±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | Mal-VC-PAB-DM1 Usage And Synthesis |
| Uses | Mal-VC-PAB-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1]. | | IC 50 | Maytansinoids | | References | [1] Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1. |
| | Mal-VC-PAB-DM1 Preparation Products And Raw materials |
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Tag:Mal-VC-PAB-DM1(1464051-44-2)
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