KDM4-IN-2 manufacturers
- KDM4-IN-2
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- $1980.00 / 50mg
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2024-10-24
- CAS:2369607-62-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | KDM4-IN-2 Basic information |
| Product Name: | KDM4-IN-2 | | Synonyms: | KDM4-IN-2;Pyrido[3,4-d]pyrimidin-4(3H)-one, 8-[4-[2-(2,3-dihydrospiro[1H-indene-1,4'-piperidin]-1'-yl)ethyl]-1H-pyrazol-1-yl]-;KDM4 IN 2,KDM-4-IN-2,KDM4IN2 | | CAS: | 2369607-62-3 | | MF: | C25H26N6O | | MW: | 426.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2369607-62-3.mol |  |
| | KDM4-IN-2 Chemical Properties |
| Boiling point | 635.8±65.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 9.43±0.20(Predicted) | | color | Light yellow to yellow |
| | KDM4-IN-2 Usage And Synthesis |
| Uses | KDM4-IN-2 (Compound 19a) is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7?nM for KDM4A and KDM5B, respectively[1]. | | IC 50 | KDM4 | | References | [1] Le Bihan YV, et al. C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur J Med Chem. 2019 Sep 1;177:316-337. DOI:10.1016/j.ejmech.2019.05.041 |
| | KDM4-IN-2 Preparation Products And Raw materials |
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