Terminolic acid manufacturers
- Terminolic acid
-
- $45.00
-
2026-05-11
- CAS:564-13-6
- Purity: 99.79%
- Supply Ability: 10g
|
| | Terminolic acid Basic information |
| Product Name: | Terminolic acid | | Synonyms: | Terminolic acid;Olean-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-;Olean-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2a,3b,4a,6b)-;racemosum,glucoside,Terminolic acid,Inhibitor,IL-1β,antibacterial,Bacterial,IL-6,triterpenoid,IL-4,inhibit,cytokines,inflammatory,pentacyclic,Combretum;(4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid;Terminolic acid, 10 mM in DMSO;2α,6β,23-trihydroxyl oleanolic acid;2α,6β,23-trihydroxyl oleanolic acid | | CAS: | 564-13-6 | | MF: | C30H48O6 | | MW: | 504.7 | | EINECS: | | | Product Categories: | | | Mol File: | 564-13-6.mol |  |
| | Terminolic acid Chemical Properties |
| Melting point | 332-334 °C | | Boiling point | 638.1±55.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 4.59±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | Terminolic acid Usage And Synthesis |
| Uses | Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity[1][1]. | | References | [1] Gossan DPA, et, al. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95. DOI:10.1016/j.fitote.2016.03.002
[2] Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147. |
| | Terminolic acid Preparation Products And Raw materials |
|