5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione

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5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione manufacturers

  • CD73-IN-3
  • CD73-IN-3 pictures
  • $58.00
  • 2026-07-27
  • CAS:2375815-63-5
  • Purity: 99.76%
  • Supply Ability: 10g
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione Basic information
Product Name:5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione
Synonyms:5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione;5-[6-Methyl-5-[(1S,2R)-2-propan-2-ylcyclopropyl]pyridazin-3-yl]-1H-pyrimidine-2,4-dione;EX-A4254;Inhibitor,cancer,CD73 IN 3,CD-73-IN-3,CD73IN3,CD73,Immunosuppression,tumor,inhibit;5-[5-[(1S,2R)-2-isopropylcyclopropyl]-6-methyl-pyridazin-3-yl]-1H-pyrimidine-2,4-dione;CD73-IN-3, 10 mM in DMSO;LY-3475070 ，S9867;CD73-IN-3
CAS:2375815-63-5
MF:C15H18N4O2
MW:286.34
EINECS:
Product Categories:
Mol File:2375815-63-5.mol
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione Structure
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione Chemical Properties
density 1.245±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (349.25 mM; Need ultrasonic)
pka7.25±0.10(Predicted)
form Solid
color White to off-white
InChIInChI=1/C15H18N4O2/c1-7(2)9-4-11(9)10-5-13(19-18-8(10)3)12-6-16-15(21)17-14(12)20/h5-7,9,11H,4H2,1-3H3,(H2,16,17,20,21)/t9-,11+/s3
InChIKeyWHRUIISQCORGKK-KEGWAHOBNA-N
SMILESC([C@H]1C[C@@H]1C1=C(N=NC(C2=CNC(=O)NC2=O)=C1)C)(C)C |&1:1,3,r|
Safety Information
MSDS Information
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione Usage And Synthesis
UsesCD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research[1].
References[1] Robert Dean Dally, et al. Cd73 inhibitors. Patent WO2019168744 A1.
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione Preparation Products And Raw materials
Tag:5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione(2375815-63-5) Related Product Information
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