NH-bis(PEG2-Boc) manufacturers
- NH-bis(PEG2-Boc)
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2025-06-07
- CAS:2182601-69-8
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | NH-bis(PEG2-Boc) Basic information |
| Product Name: | NH-bis(PEG2-Boc) | | Synonyms: | NH-bis(PEG2-Boc);NH-bis(C2-PEG2-NH-Boc);5,8,14,17-Tetraoxa-2,11,20-triazaheneicosanedioic acid, 1,21-bis(1,1-dimethylethyl) ester;Di-tert-butyl (3,6,12,15-tetraoxa-9-azaheptadecane-1,17-diyl)dicarbamate;HN-(PEG2-CH2CH2NHBoc)2;BocNH-PEG3-NH-PEG3-HNBoc | | CAS: | 2182601-69-8 | | MF: | C22H45N3O8 | | MW: | 479.61 | | EINECS: | | | Product Categories: | | | Mol File: | 2182601-69-8.mol |  |
| | NH-bis(PEG2-Boc) Chemical Properties |
| Boiling point | 577.0±50.0 °C(Predicted) | | density | 1.064±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Soluble in Water, DMSO, DMF, DCM | | pka | 11.93±0.46(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | NH-bis(PEG2-Boc) Usage And Synthesis |
| Description | NH-bis(PEG2-Boc) is a Boc protected amine molecule whiich is reactive with carboxylic acids, activated NHS esters,. Boc can be deprotected under acidic conditions. | | Uses | NH-bis(C2-PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | NH-bis(PEG2-Boc) Preparation Products And Raw materials |
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