Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro-

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Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro- Basic information
Product Name:Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro-
Synonyms:Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro-;(-)-N-Trifluoroacetyl-1-aminoindan;Rasagiline Impurity 20
CAS:155666-94-7
MF:C11H10F3NO
MW:229.2
EINECS:
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Mol File:155666-94-7.mol
Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro- Structure
Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro- Chemical Properties
Boiling point 317.8±42.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
pka10.44±0.20(Predicted)
Safety Information
MSDS Information
Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro- Usage And Synthesis
Uses(-)-N-Trifluoroacetyl-1-aminoindan is an intermediate in the synthesis of (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one (D449765), which is a building block in the preparation of Rasagiline (R126000), which is a selective irreversible MAO-B inhibitor. Rasagiline is also an Antiparkinsonian agent.
Acetamide, N-[(1R)-2,3-dihydro-1H-inden-1-yl]-2,2,2-trifluoro- Preparation Products And Raw materials
Raw materials(R)-(-)-1-Aminoindan-->Trifluoroacetic anhydride
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