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2-Nitrobenzyl alcohol

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2-Nitrobenzyl alcohol Basic information
Uses
Product Name:2-Nitrobenzyl alcohol
Synonyms:RARECHEM AL BD 0186;O-NITROBENZYL ALCOHOL;O-NITROPHENYLCARBINOL;LABOTEST-BB LT01997457;(2-NITROPHENYL)METHANOL;2-NITROBENZYL ALCOHOL;2-nitro-benzenemethano;2-nitrobenzenemethanol
CAS:612-25-9
MF:C7H7NO3
MW:153.14
EINECS:210-302-6
Product Categories:Alcohols;C7 to C8;Oxygen Compounds;john's;ADVANCED INT.
Mol File:612-25-9.mol
2-Nitrobenzyl alcohol Structure
2-Nitrobenzyl alcohol Chemical Properties
Melting point 69-72 °C(lit.)
Boiling point 270 °C(lit.)
density 1.3386 (rough estimate)
refractive index 1.5030 (estimate)
Fp 168°C/20mm
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
pka13.77±0.10(Predicted)
form Crystalline Powder
color Beige to beige-brown
Water Solubility Soluble in water 5000 mg/L 20 deg Celsius.
Sensitive Light Sensitive
BRN 2046649
InChI1S/C7H7NO3/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4,9H,5H2
InChIKeyBWRBVBFLFQKBPT-UHFFFAOYSA-N
SMILESOCc1ccccc1[N+]([O-])=O
CAS DataBase Reference612-25-9(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenemethanol, 2-nitro-(612-25-9)
Safety Information
Hazard Codes Xi,C,F
Risk Statements 11-34
Safety Statements 22-24/25-45-36/37/39-26-16
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DP0657050
Hazard Note Irritant
HS Code 29062900
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
2-Nitrobenzyl alcohol English
ACROS English
SigmaAldrich English
ALFA English
2-Nitrobenzyl alcohol Usage And Synthesis
Uses2-Nitrobenzyl alcohol is a useful research chemical.
Chemical Propertieswhite to light yellow crystal powde
UsesThe o-nitrobenzyl group (o-NB) is utilized frequently in polymer and materials science. It covers the use of based cross-linkers for photodegradable hydrogels, o-NB side chain functionalization in (block) copolymers, o-NB side chain functionalization for thin film patterning, o-NB for self-assembled monolayers, photo cleavable block copolymers, and photo cleavable bioconjugates.
Synthesis
Silane, trimethyl[(2-nitrophenyl)methoxy]-

62673-13-6

2-Nitrobenzyl alcohol

612-25-9

GENERAL METHODS: The substrate (1 mmol, CAS: 62673-13-6) was mixed with ionic liquid [Dsim]HSO4 (6.5 mg, ~0.02 mmol) in methanol (2 mL) and the reaction was stirred at room temperature. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by evaporation and water (1 mL) was added to the residue with vigorous stirring. The almost pure o-nitrobenzyl alcohol product was obtained by decantation separation. The structure of the product was characterized by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR) data. The ionic liquid was recovered for reuse after vacuum drying at 65 °C to remove water.

storageLight-sensitive. Harmful if swallowed or inhaled.
References[1] Bulletin of the Chemical Society of Japan, 2000, vol. 73, # 12, p. 2775 - 2778
[2] Journal of Molecular Catalysis A: Chemical, 2012, vol. 365, p. 15 - 23
[3] Journal of Chemical Research, 2006, # 1, p. 29 - 31
[4] Phosphorus, Sulfur and Silicon and the Related Elements, 2008, vol. 183, # 1, p. 168 - 177
[5] Journal of the Chinese Chemical Society, 2008, vol. 55, # 5, p. 943 - 946
2-Nitrobenzyl alcohol Preparation Products And Raw materials
Raw materialsSodium carbonate-->Bromine-->2-Nitrotoluene-->2-Nitrobenzaldehyde-->Silane, trimethyl[(2-nitrophenyl)methoxy]-
Preparation ProductsMETHYL 2-NITROBENZOATE
Tag:2-Nitrobenzyl alcohol(612-25-9) Related Product Information
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