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3-Amino-4-methylphenol

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3-Amino-4-methylphenol manufacturers

  • 3-Amino-4-methylphenol
  • 3-Amino-4-methylphenol pictures
  • $0.00 / 1KG
  • 2026-04-23
  • CAS:2836-00-2
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 30tons/month
  • p-Cresol, 3-amino-
  • p-Cresol, 3-amino- pictures
  • $2.20 / 1000kg
  • 2026-04-17
  • CAS:2836-00-2
  • Min. Order: 1kg
  • Purity: 99%min
  • Supply Ability: 1000kg
3-Amino-4-methylphenol Basic information
Product Name:3-Amino-4-methylphenol
Synonyms:3-amino-p-cresol;3-AMINO-4-METHYLPHENOL;5-Hydroxy-o-toluidine;2-AMINO-4-HYDROXYTOLUENE;5-Hydroxy-2-methylaniline;m-Amino-p-cresol;2-aMino-4-hydroxytoluene, 98%+;3-Amino-4-Methylphenol 98%
CAS:2836-00-2
MF:C7H9NO
MW:123.15
EINECS:220-622-8
Product Categories:pharmacetical;Phenol&Thiophenol&Mercaptan
Mol File:2836-00-2.mol
3-Amino-4-methylphenol Structure
3-Amino-4-methylphenol Chemical Properties
Melting point 156-157°C
Boiling point 229.26°C (rough estimate)
density 1.0877 (rough estimate)
refractive index 1.5706 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka10.32±0.18(Predicted)
form powder to crystal
color Light yellow to Brown to Dark green
CAS DataBase Reference2836-00-2(CAS DataBase Reference)
EPA Substance Registry System3-Amino-4-methylphenol (2836-00-2)
Safety Information
Hazard Codes Xi
Hazard Note Irritant
HS Code 2922290090
MSDS Information
ProviderLanguage
5-Hydroxy-o-toluidine English
3-Amino-4-methylphenol Usage And Synthesis
General DescriptionCrystals.
Air & Water Reactions3-Amino-4-methylphenol may be sensitive to prolonged exposure to air.
Reactivity Profile3-Amino-4-methylphenol reacts with strong oxidizing agents.
Fire HazardFlash point data for 3-Amino-4-methylphenol are not available. 3-Amino-4-methylphenol is probably combustible.
Synthesis
4-Methyl-3-nitrophenol

2042-14-0

3-Amino-4-methylphenol

2836-00-2

The general procedure for the synthesis of 3-amino-4-methylphenol from 4-methyl-3-nitrophenol was as follows: 4-methyl-3-nitrophenol (77 mg, 0.50 mmol), Fe nanoparticles (6 mg), and NaBH4 (29 mg, 0.75 mmol) were placed in 1.0 mL of 2 wt. % TPGS/H2O solution, and the reaction was carried out for 2 h at room temperature. Upon completion of the reaction, 56 mg (91% yield) of 3-amino-4-methylphenol was obtained as a white solid (hexane/ethyl acetate = 50:50). The melting point of the product was 154°C-156°C. It was analyzed by GC-MS with m/z of 123 [M], and the spectral data were consistent with those reported in the literature.

References[1] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 1, p. 240 - 244
[2] Green Chemistry, 2017, vol. 19, # 3, p. 809 - 815
[3] Journal of Medicinal Chemistry, 2010, vol. 53, # 5, p. 1964 - 1978
[4] ACS Catalysis, 2017, vol. 7, # 4, p. 2412 - 2418
[5] Patent: WO2018/208132, 2018, A1. Location in patent: Paragraph 704-708
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