- 3-Amino-4-methylphenol
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- $0.00 / 1KG
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2025-10-22
- CAS:2836-00-2
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- 3-Amino-4-methylphenol
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- $10.00 / 1KG
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2025-10-21
- CAS:2836-00-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- p-Cresol, 3-amino-
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- $2.20 / 1000kg
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2025-10-13
- CAS:2836-00-2
- Min. Order: 1kg
- Purity: 99%min
- Supply Ability: 1000kg
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| | 3-Amino-4-methylphenol Basic information |
| | 3-Amino-4-methylphenol Chemical Properties |
| Melting point | 156-157°C | | Boiling point | 229.26°C (rough estimate) | | density | 1.0877 (rough estimate) | | refractive index | 1.5706 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 10.32±0.18(Predicted) | | form | powder to crystal | | color | Light yellow to Brown to Dark green | | CAS DataBase Reference | 2836-00-2(CAS DataBase Reference) | | EPA Substance Registry System | 3-Amino-4-methylphenol (2836-00-2) |
| Hazard Codes | Xi | | Hazard Note | Irritant | | HS Code | 2922290090 |
| | 3-Amino-4-methylphenol Usage And Synthesis |
| General Description | Crystals. | | Air & Water Reactions | 3-Amino-4-methylphenol may be sensitive to prolonged exposure to air. | | Reactivity Profile | 3-Amino-4-methylphenol reacts with strong oxidizing agents. | | Fire Hazard | Flash point data for 3-Amino-4-methylphenol are not available. 3-Amino-4-methylphenol is probably combustible. | | Synthesis | The general procedure for the synthesis of 3-amino-4-methylphenol from 4-methyl-3-nitrophenol was as follows: 4-methyl-3-nitrophenol (77 mg, 0.50 mmol), Fe nanoparticles (6 mg), and NaBH4 (29 mg, 0.75 mmol) were placed in 1.0 mL of 2 wt. % TPGS/H2O solution, and the reaction was carried out for 2 h at room temperature. Upon completion of the reaction, 56 mg (91% yield) of 3-amino-4-methylphenol was obtained as a white solid (hexane/ethyl acetate = 50:50). The melting point of the product was 154°C-156°C. It was analyzed by GC-MS with m/z of 123 [M], and the spectral data were consistent with those reported in the literature. | | References | [1] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 1, p. 240 - 244
[2] Green Chemistry, 2017, vol. 19, # 3, p. 809 - 815
[3] Journal of Medicinal Chemistry, 2010, vol. 53, # 5, p. 1964 - 1978
[4] ACS Catalysis, 2017, vol. 7, # 4, p. 2412 - 2418
[5] Patent: WO2018/208132, 2018, A1. Location in patent: Paragraph 704-708 |
| | 3-Amino-4-methylphenol Preparation Products And Raw materials |
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