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| | CEK10 /FC CHIMERA Basic information |
| Product Name: | CEK10 /FC CHIMERA | | Synonyms: | Monoclonal Anti-EPHB3 antibody produced in mouse;ANTI-EPHB3 antibody produced in mouse;TYRO6/FC CHIMERA;Cek10;Mdk5;Tyro6;CEK10 /FC CHIMERA;EPHB3/FC CHIMERA | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CEK10 /FC CHIMERA Structure]() |
| | CEK10 /FC CHIMERA Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | mouse | | Specific Activity | 22-30nmol/min·mg |
| WGK Germany | 3 | | Storage Class | 10 - Combustible liquids |
| | CEK10 /FC CHIMERA Usage And Synthesis |
| Uses | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. (provided by RefSeq) | | General Description | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. (provided by RefSeq) | | Biological Activity | EPHB3 is a member of the Ephrin receptor family and is expressed during embryonic development in multiple regions of the central nervous system. In adult brain, EPHB3 is expressed in the cerebellum, raphe pallidus, hippocampus, entorhinal cortex, and both motor and sensory cortices. EPHB3 is involved in the maintenance of mature neuronal connections and/or re-arrangement of synaptic connections during late stages of development. EPHB3 plays a role in the regulation of cell adhesion and migration, and the catalytic activity of EPHB3 is required for inhibition of integrin-mediated cell adhesion. |
| | CEK10 /FC CHIMERA Preparation Products And Raw materials |
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