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| | APOLIPOPROTEIN C-I, HUMAN Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | human |
| Hazard Codes | B | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | APOLIPOPROTEIN C-I, HUMAN Usage And Synthesis |
| Uses | Apolipoprotein C-1 directly interferes with fatty acid uptake and is a major plasma inhibitor of cholesterol ester transfer protein. Apolipoprotein C-I has been used to develop a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice. | | Biological Activity | Interferes directly with fatty acid uptake and is the major plasma inhibitor of cholesterol ester transfer protein. | | Description | APOC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 80 amino acids (27-83 a.a.) and having a molecular mass of 9.0kDa. APOC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | Apolipoprotein C-I (APOC1) which expressed mainly in the liver is a part of the apolipoprotein C family. APOC1 which is usually found in plasma and responsible for the activation of esterified lechitin cholesterol takes an important part in the exchange of esterified cholesterol among lipoproteins and in removal of cholesterol from tissues. APOC1 is activated when monocytes differentiate into macrophages. APOC1 protein’s main role is to inhibit CETP by altering the electric charge of HDL molecules. APOC1 is also binds free fatty acids and reduces their intracellular esterification. |
| | APOLIPOPROTEIN C-I, HUMAN Preparation Products And Raw materials |
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