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| | 2'-Deoxycytidine-5'-monophosphoric acid Basic information |
| | 2'-Deoxycytidine-5'-monophosphoric acid Chemical Properties |
| Melting point | 169-172 °C (dec.) | | Boiling point | 633.8±65.0 °C(Predicted) | | density | 2.01±0.1 g/cm3(Predicted) | | refractive index | 37 ° (C=1, H2O) | | storage temp. | -20°C | | solubility | H2O: 10 mg/mL, clear, colorless | | form | Crystalline Powder | | pka | 1.86±0.10(Predicted) | | color | White | | biological source | synthetic | | Water Solubility | Soluble in water. | | BRN | 41062 | | InChI | InChI=1S/C9H14N3O7P/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1 | | InChIKey | NCMVOABPESMRCP-SHYZEUOFSA-N | | SMILES | P(OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)C[C@@H]1O)(O)(O)=O | | CAS DataBase Reference | 1032-65-1(CAS DataBase Reference) |
| | 2'-Deoxycytidine-5'-monophosphoric acid Usage And Synthesis |
| Chemical Properties | Crystalline | | Uses | A phosphorylated metabolite of the deoxyribonucleoside 2’Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferatio
n. | | Uses | 2'-Deoxycytidine-5'-monophosphate is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA and RNA biosynthesis. | | Definition | ChEBI: Dianion of 2'-deoxycytidine 5'-monophosphate arising from deprotonation of both OH groups of the phosphate. | | General Description | 2′-Deoxycytidine 5′-monophosphate is a deoxynucleotide building block via which DNA is made. It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine. It is phosphorylated at carbon C-5′. | | Purification Methods | Recrystallise the acid from H2O or aqueous EtOH and dry it in a vacuum. [Volkin et al. J Am Chem Soc 73 1533 1951, UV: Fox et al. J Am Chem Soc 75 4315 1953, IR: Michelson & Todd J Chem Soc 3438 1954, Beilstein 25 IV 3664.] |
| | 2'-Deoxycytidine-5'-monophosphoric acid Preparation Products And Raw materials |
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