Chlorogentisyl alcohol manufacturers
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| | Chlorogentisyl alcohol Basic information |
| Product Name: | Chlorogentisyl alcohol | | Synonyms: | AMUDOL;2-(Hydroxymethyl)-6-chlorohydroquinone;2,5-Dihydroxy-3-chlorobenzyl alcohol;2-Chloro-6-(hydroxymethyl)-1,4-benzenediol;3-Chloro-2,5-dihydroxybenzyl alcohol;3-Chlorogentisyl alcohol;1,4-Benzenediol, 2-chloro-6-(hydroxymethyl)-;Chlorogentisyl alcohol | | CAS: | 32744-80-2 | | MF: | C7H7ClO3 | | MW: | 174.58 | | EINECS: | | | Product Categories: | | | Mol File: | 32744-80-2.mol |  |
| | Chlorogentisyl alcohol Chemical Properties |
| Melting point | 105-106 °C | | Boiling point | 311.641±22.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.558±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | solubility | DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly Soluble: 1-10 mg/ml | | pka | 9.185±0.23(predicted) | | form | Solid | | color | Off-white to light yellow |
| | Chlorogentisyl alcohol Usage And Synthesis |
| Uses | 3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 μM, an Ki value of 0.58 μM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1]. | | References | [1] YichaoGe， et al. Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches. European Journal of Medicinal Chemistry, 2022, 114699.
[2] THERESA FUK NING KWONG. Novel Antifouling and Antimicrobial Compound from a Marine-Derived Fungus Ampelomyces sp.[J]. Marine Biotechnology, 2006, 8 6: 634-640. DOI: 10.1007/s10126-005-6146-2
[3] YONG LI. New radical scavenging and ultraviolet-A protecting prenylated dioxopiperazine alkaloid related to isoechinulin A from a marine isolate of the fungus Aspergillus.[J]. Journal of Antibiotics, 2004, 57 5: 337-340. DOI: 10.7164/antibiotics.57.337
[4] YANJUN ZHANG. 3-Chloro-2,5-dihydroxybenzyl alcohol activates human cervical carcinoma HeLa cell apoptosis by inducing DNA damage.[J]. International journal of oncology, 2007, 31 6: 1317-1323. |
| | Chlorogentisyl alcohol Preparation Products And Raw materials |
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