- 2-Methoxythiophene
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- $9.90 / 1KG
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2026-03-20
- CAS:16839-97-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 2-Methoxythiophene
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- $1.10 / 1g
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2025-11-18
- CAS:16839-97-7
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons
- 2-Methoxythiophene
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- $200.00 / 1KG
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2025-09-25
- CAS:16839-97-7
- Min. Order: 1KG
- Purity: 99%, 99.5% Sublimated
- Supply Ability: g-kg-tons, free sample is available
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| | 2-Methoxythiophene Basic information |
| | 2-Methoxythiophene Chemical Properties |
| Boiling point | 151-152 °C/762 mmHg (lit.) | | density | 1.133 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.528(lit.) | | Fp | 110 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform, Methanol (Slightly) | | form | clear liquid | | color | Colorless to Light yellow to Light orange | | BRN | 106271 | | InChI | InChI=1S/C5H6OS/c1-6-5-3-2-4-7-5/h2-4H,1H3 | | InChIKey | OKEHURCMYKPVFW-UHFFFAOYSA-N | | SMILES | C1(OC)SC=CC=1 | | LogP | 2.130 | | CAS DataBase Reference | 16839-97-7(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Methoxythiophene(16839-97-7) |
| Risk Statements | 10 | | Safety Statements | 16 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29349990 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Flam. Liq. 3 |
| | 2-Methoxythiophene Usage And Synthesis |
| Chemical Properties | CLEAR YELLOW LIQUID | | Uses | 2-Methoxythiophene was used in thermal reaction (60°C) of (C5Me5)Rh(PMe3)(Ph)H. | | Synthesis Reference(s) | Journal of the American Chemical Society, 75, p. 3697, 1953 DOI: 10.1021/ja01111a027 | | General Description | 2-Methoxythiophene is a heterocyclic methyl enol ether and its reaction with o-quinone monoimide was studied. The intramolecular and intermolecular geometries of crystals of 2-methoxythiophene were investigated. Kinetics of the hydronium-ion catalysed hydrolysis of 2-methoxythiophene was reported. | | Synthesis | Example 1 Preparation of 2-methoxythiophene: In a reactor, 300 g of 2-bromothiophene (1.84 mol), 2.64 g of copper(I) bromide (CuBr, 1 mol%), 18.4 g of polyethylene glycol dimethyl ether (PEG DME 500, 2 mol%), and 660 g of a methanolic solution of sodium methanolate (30% concentration, precursor concentration of 30.6%) were added in sequence. The mixture was heated to 90 °C for the reaction and the progress of the reaction was monitored by gas chromatography (GC) until the conversion was >98% (total reaction time 8h). Upon completion of the reaction, the reaction mixture was slowly poured into 500 g of water and filtered through Decalite. Subsequently, the aqueous phase was extracted twice with methyl tert-butyl ether (MTBE, 150 g each time). The organic phases were combined and purified by vacuum fractional distillation to give a final 182 g of 2-methoxythiophene (1.59 mol, 86.4% yield) with a GC purity of >99% (% area). | | References | [1] Patent: US2008/71084, 2008, A1. Location in patent: Page/Page column 3-4
[2] Synthetic Communications, 1990, vol. 20, # 2, p. 213 - 216
[3] Tetrahedron, 1992, vol. 48, # 17, p. 3633 - 3652
[4] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8651 - 8664 |
| | 2-Methoxythiophene Preparation Products And Raw materials |
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