- Caulophyllogenin
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- $113.00 / 1mg
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2026-01-29
- CAS:52936-64-8
- Min. Order:
- Purity: 99.69%
- Supply Ability: 10g
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| | CAULOPHYLLOGENIN Basic information |
| Product Name: | CAULOPHYLLOGENIN | | Synonyms: | (3beta,4alpha,16alpha)-3,16,23-trihydroxyolean-12-en-28-oic acid;CAULOPHYLLOGENIN hplc;CAULOPHYLLOGENIN WITH HPLC;(4R)-3β,16α,23-Trihydroxyolean-12-en-28-oic acid;3β,16α,23-Trihydroxyoleana-12-ene-28-oic acid;Segetalic acid;(3β,4α,16α)-3,16,23-trihydroxyolean-12-en-28-oic acid;3BETA, 16ALPHA, 23-TRIHYDROXYOLEAN-12-ENE 28-OIC ACID | | CAS: | 52936-64-8 | | MF: | C30H48O5 | | MW: | 488.7 | | EINECS: | 258-265-5 | | Product Categories: | Tri-Terpenoids | | Mol File: | 52936-64-8.mol |  |
| | CAULOPHYLLOGENIN Chemical Properties |
| Melting point | >300°C (dec.) | | Boiling point | 621.5±55.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 4.42±0.70(Predicted) | | LogP | 5.930 (est) |
| | CAULOPHYLLOGENIN Usage And Synthesis |
| Chemical Properties | Caulophyllogenin is an important commercial chemical that is widely used in the manufacture of rubber hardeners, electroplating additives, skin antiseptic bactericides, hair dyes, photographic developers, etc. Pesticide intermediates of propoxur and carbocarb. | | Uses | Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50of12.6μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation[1][2]. | | Definition | ChEBI: Caulophyllogenin is a triterpenoid. | | Biological Activity | Caulophyllogenin is a triterpenoid saponin extracted from M. polimorpha. It is a partial agonist of PPARγ with an EC50 value of 12.6 μM. Caulophyllogenin can be used to study type 2 diabetes, obesity, metabolic syndrome and inflammation. | | IC 50 | PPARγ: 12.6 μM (EC50) | | References | [1] Montanari R, et, al. Screening of saponins and sapogenins from Medicago species as potential PPARγ agonists and X-ray structure of the complex PPARγ/caulophyllogenin. Sci Rep. 2016 Jun 10; 6:27658. DOI:10.1038/srep27658
[2] Zhang Y, et, al. Studies on cytotoxic triterpene saponins from the leaves of Aralia elata. Food Chem. 2013 May 1;138(1):208-13. DOI:10.1016/j.foodchem.2012.10.041 |
| | CAULOPHYLLOGENIN Preparation Products And Raw materials |
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