| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:MRT00033659
CAS:1401731-54-1
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:MRT00033659
CAS:1401731-54-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
MRT00033659 manufacturers
- MRT00033659
-
- $68.00 / 2mg
-
2026-01-04
- CAS:1401731-54-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | MRT00033659 Basic information |
| Product Name: | MRT00033659 | | Synonyms: | MRT00033659;Acetamide, N-[3-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]-;MRT-00033659,MRT00033659 | | CAS: | 1401731-54-1 | | MF: | C15H14N4O | | MW: | 266.3 | | EINECS: | | | Product Categories: | | | Mol File: | 1401731-54-1.mol |  |
| | MRT00033659 Chemical Properties |
| Boiling point | 585.6±50.0 °C(Predicted) | | density | 1.312±0.06 g/cm3(Predicted) | | form | Solid | | pka | 9.99±0.40(Predicted) | | color | Off-white to light yellow |
| | MRT00033659 Usage And Synthesis |
| Uses | MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 (IC50=0.9 μM for CK1δ) and CHK1 (IC50=0.23 μM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisation[1]. | | IC 50 | CKIδ: 0.9 μM (IC50); Chk1: 0.23 μM (IC50) | | References | [1] Huart AS, et al. A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novelactivator of the p53 pathway. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5578-85. DOI:10.1016/j.bmcl.2013.08.046 |
| | MRT00033659 Preparation Products And Raw materials |
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