| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
13636370518 |
| Email: |
shyysw007@163.com |
| Products Intro: |
Product Name:Rozanolixizumab (anti-FCGRT) CAS:1584645-37-3 Purity:Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human I Package:100μg Remarks:K13588
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| Company Name: |
ShangHai Biochempartner Co.,Ltd
|
| Tel: |
177-54423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:Rozanolixizumab CAS:1584645-37-3 Purity:95% Package:100ug;500ug;1mg
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| Company Name: |
Guangzhou Hongyuan Chemical Co.,Ltd
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| Tel: |
15817493340 |
| Email: |
981810490@qq.com |
| Products Intro: |
Product Name:Rozanolixizumab CAS:1584645-37-3 Purity:95% Package:1mg;1g;100g
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Rozanolixizumab manufacturers
- Rozanolixizumab
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- $228.00
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2026-07-27
- CAS:1584645-37-3
- Purity: 97.2% (SDS-PAGE); 95.9% (SEC-HPLC)
- Supply Ability: 10g
- Rozanolixizumab
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2026-07-13
- CAS:1584645-37-3
- Min. Order: 1g
- Purity: 98
- Supply Ability: 1000g
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| | Rozanolixizumab Basic information |
| Product Name: | Rozanolixizumab | | Synonyms: | Rozanolixizumab;Research Grade Rozanolixizumab(DHF14602);UCB7665;UCB-7665;Research Grade Rozanolixizumab;Rozanolixizumab (anti-FCGRT) | | CAS: | 1584645-37-3 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Rozanolixizumab Structure]() |
| | Rozanolixizumab Chemical Properties |
| storage temp. | Store at -20°C | | form | Liquid | | color | Colorless to light yellow |
| | Rozanolixizumab Usage And Synthesis |
| Uses | Rozanolixizumab (UCB7665), a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases[1]. | | in vivo | Intravenous (IV) rozanolixizumab dosing in cynomolgus monkeys demonstrated non-linear pharmacokinetics indicative of target-mediated drug disposition; single IV rozanolixizumab doses (30 mg/kg) in cynomolgus monkeys reduced plasma IgG concentration by 69% by Day 7 post-administration. Daily IV administration of rozanolixizumab (initial 30 mg/kg loading dose; 5 mg/kg daily thereafter) reduced plasma IgG concentrations in all cynomolgus monkeys, with low concentrations maintained throughout the treatment period (42 days)[1]. | | References | [1] Smith B, et al. Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. MAbs. 2018;10(7):1111-1130. DOI:10.1080/19420862.2018.1505464 |
| | Rozanolixizumab Preparation Products And Raw materials |
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