ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Dihydropyridine >tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate

tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate

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tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Suppliers list
Company Name: Eaglech（shanghai）Pharmaceutical Co., Ltd
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Products Intro: Product Name:ter-butyl 2,4-dichloro-5,6-dihydropyido[3,4-d]pyrimidine-7(8H)-carboxylate
CAS:916420-27-4
Purity:98.5% Package:1KG;6000USD
Company Name: Lianhe Aigen Pharmatech Co.,Ltd.
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Products Intro: Product Name:tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate
CAS:916420-27-4
Purity:97% Package:10g, 50g, 100g ,500g,1kg
Company Name: ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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Products Intro: Product Name:tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate
CAS:916420-27-4
Purity:99% Package:100kg;2USD|10kg;4USD|1kg;6USD
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Tert-butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
CAS:916420-27-4
Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
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Products Intro: Product Name:tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
CAS:916420-27-4
Purity:99% Package:1KG,5KG,10KG

tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate manufacturers
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Basic information
Product Name:tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
Synonyms:tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate 7-Boc-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine;tert-butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate;tert-butyl 2,4-dichloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxylate;TERT-BUTYL 2,4-DICHLORO-5,6-DIHYDROPYRIDO[3,4-D]PYRIMIDINE-7(8H)-CARBOXYLATE;7-Boc-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine;tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate;2,4-Dichloro-7-Boc-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine;7-Boc-2,4-dichloro-5,6,7,...
CAS:916420-27-4
MF:C12H15Cl2N3O2
MW:304.17
EINECS:1533716-785-6
Product Categories:Heterocycle-Pyrimidine series;CHIRAL CHEMICALS;916420-27-4
Mol File:916420-27-4.mol
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Structure
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Chemical Properties
Boiling point 423.1±45.0 °C(Predicted)
density 1.352±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka-1.95±0.20(Predicted)
AppearanceWhite to light yellow Solid
InChIInChI=1S/C12H15Cl2N3O2/c1-12(2,3)19-11(18)17-5-4-7-8(6-17)15-10(14)16-9(7)13/h4-6H2,1-3H3
InChIKeySAEOMPAQDWZLHC-UHFFFAOYSA-N
SMILESC1(Cl)=NC(Cl)=C2CCN(C(OC(C)(C)C)=O)CC2=N1
Safety Information
HS Code 2933998090
MSDS Information
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Usage And Synthesis
Uses tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate (tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate) can be used as an intermediate for laboratory R&D.
Synthesistert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate can be prepared by Intermediate 4 in DCM stirred with (Boc)2O and TEA at room temperature for 16 hours.
Synthesis_916420-27-4
References[1] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 174; 175
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Preparation Products And Raw materials
Raw materialsDi-tert-butyl dicarbonate-->2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl salt-->Dichloromethane-->Triethylamine
Tag:tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate(916420-27-4) Related Product Information
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