Benzenemethanol, 4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]-2-chloro- manufacturers
- PD-89211
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- $2500.00
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2026-04-21
- CAS:444725-49-9
- Purity:
- Supply Ability: 10g
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| | Benzenemethanol, 4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]-2-chloro- Basic information |
| | Benzenemethanol, 4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]-2-chloro- Chemical Properties |
| Boiling point | 639.0±55.0 °C(Predicted) | | density | 1.359±0.06 g/cm3(Predicted) | | pka | 11.83±0.10(Predicted) |
| | Benzenemethanol, 4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]-2-chloro- Usage And Synthesis |
| Uses | PD-89211 is a selective dopamine D4 receptor antagonist with a Ki value of 3.7 nM. PD-89211 reverses Quinpirole (HY-B1752A)-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM). PD-89211 regulates dopamine/norepinephrine metabolism in the hippocampus and can be used for research on central nervous system disorders such as schizophrenia[1]. | | References | [1] Pugsley TA, et al. The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Feb;26(2):219-26. DOI:10.1016/s0278-5846(01)00252-4 |
| | Benzenemethanol, 4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]-2-chloro- Preparation Products And Raw materials |
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