|
|
| | N-(4-Nitrophenyl)propionamide Basic information |
| Product Name: | N-(4-Nitrophenyl)propionamide | | Synonyms: | P-NITRO PROPIONANILIDE;P-NITRO-PROPIONYLANILIDE;N-(4-NITROPHENYL)PROPIONAMIDE;3-NITRO PROPIONANILIDE;4-Nitro-propionylanilide;Nitro propionyl aniline;N-(4-Nitrophenyl);Propanamide, N-(4-nitrophenyl)- | | CAS: | 4850-93-5 | | MF: | C9H10N2O3 | | MW: | 194.19 | | EINECS: | | | Product Categories: | | | Mol File: | 4850-93-5.mol |  |
| | N-(4-Nitrophenyl)propionamide Chemical Properties |
| Melting point | 182 °C | | Boiling point | 411.7±28.0 °C(Predicted) | | density | 1.287±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 13.91±0.70(Predicted) |
| | N-(4-Nitrophenyl)propionamide Usage And Synthesis |
| Synthesis | General procedure for the synthesis of p-nitropropionanilide from propionyl chloride and 4-nitroanilide: To a solution of 4-nitroanilide (7.5 mmol, 1.04 g) in dichloromethane (30 mL) was slowly added propionyl chloride (7.5 mmol, 0.70 mL). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was filtered and the filtrate was concentrated under reduced pressure by rotary evaporator to remove the solvent. The crude product was washed with hexane (10 mL) to remove impurities. Finally, the product was dried under vacuum to afford the target compound N-(4-nitrophenyl)propionamide in white powder form in a yield of 0.38 g (26% yield). | | References | [1] Dalton Transactions, 2014, vol. 43, # 23, p. 8888 - 8893
[2] Patent: US2014/228579, 2014, A1. Location in patent: Paragraph 0155
[3] Pest Management Science, 2000, vol. 56, # 7, p. 607 - 614
[4] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 23, p. 10034 - 10042
[5] Patent: WO2010/129053, 2010, A2. Location in patent: Page/Page column 112-113 |
| | N-(4-Nitrophenyl)propionamide Preparation Products And Raw materials |
|