YGSY2P-IN-H23
| 中文名称 | YGSY2P-IN-H23 |
|---|---|
| 中文同义词 | |
| 英文名称 | Phenol, 2-methoxy-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-phenyl-1H-imidazol-5-yl]- |
| 英文同义词 | Phenol, 2-methoxy-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-phenyl-1H-imidazol-5-yl]-;yGsy2p-IN-H23 |
| CAS号 | 1269190-98-8 |
| 分子式 | C23H27N3O2 |
| 分子量 | 377.48 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1269190-98-8.mol |
| 结构式 |  |
YGSY2P-IN-H23 性质
| 沸点 | 545.8±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.19±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 形态 | 固体 |
| 酸度系数(pKa) | 9.72±0.20(Predicted) |
| 颜色 | 米白色至棕色 |
yGsy2p-IN-H23 是一种有效的酵母糖原合酶 2 (yGsy2p) 抑制剂，对人糖原合酶 1 (hGYS1) 的 IC50 为 875 µM。yGsy2p-IN-H23 结合在 yGsy2p 的尿苷二磷酸葡萄糖结合口袋内。yGsy2p-IN-H23 用于糖原储存疾病 (GSDs) 的相关研究。
IC50: 875 µM (hGYS1)
yGsy2p-IN-H23 (compound H23) has IC 50 values against either hGYS1Δ634S8,11N or wild-type hGYS1 were 161 μM and 875 µM, respectively. yGsy2p-IN-H23 exhibits IC 50 values of 280 µM and 263 µM in the absence and presence of G6P for yGsy2p against yeast and human glycogen synthase (GS), respectively. yGsy2p-IN-H23 is not in direct competition with G6P.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-131177 | yGsy2p-IN-H23 | 1269190-98-8 | 5mg | 2000元 |
| 2025/12/22 | HY-131177 | yGsy2p-IN-H23 | 1269190-98-8 | 10mM * 1mLin DMSO | 2200元 |