| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:PD159790
CAS:179598-53-9
Package:25mg/RMB 11700;100mg/RMB 19500;50mg/RMB 15300
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4-Quinazolinamine, N-(1-ethyl-3-piperidinyl)-6-iodo-2-(trifluoromethyl)- manufacturers
- PD159790
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- $1670.00 / 25mg
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2026-01-05
- CAS:179598-53-9
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 4-Quinazolinamine, N-(1-ethyl-3-piperidinyl)-6-iodo-2-(trifluoromethyl)- Basic information |
| | 4-Quinazolinamine, N-(1-ethyl-3-piperidinyl)-6-iodo-2-(trifluoromethyl)- Chemical Properties |
| Boiling point | 397.9±42.0 °C(Predicted) | | density | 1.630±0.06 g/cm3(Predicted) | | pka | 8.59±0.10(Predicted) |
| | 4-Quinazolinamine, N-(1-ethyl-3-piperidinyl)-6-iodo-2-(trifluoromethyl)- Usage And Synthesis |
| Uses | PD159790 is a selective endothelin-converting enzyme-1 (ECE-1) inhibitor, with an EC50 of 28.1 μM[1][2][3]. | | References | [1] Janet Maguire, et al. Alternative pathway to endothelin-converting enzyme for the synthesis of endothelin in human blood vessels. J Cardiovasc Pharmacol. 2004 Nov:44 Suppl 1:S27-9. DOI:10.1097/01.fjc.0000166219.65593.af
[2] F D Russell, et al. Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells. Circ Res. 1999 Apr 30;84(8):891-6. DOI:10.1161/01.res.84.8.891
[3] K Ahn, et al. Novel selective quinazoline inhibitors of endothelin converting enzyme-1. Biochem Biophys Res Commun. 1998 Feb 4;243(1):184-90. DOI:10.1006/bbrc.1998.8081 |
| | 4-Quinazolinamine, N-(1-ethyl-3-piperidinyl)-6-iodo-2-(trifluoromethyl)- Preparation Products And Raw materials |
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