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| | 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE Basic information |
| Product Name: | 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE | | Synonyms: | 4-AMINOMETHYL-3,5-DIMETHYLISOXAZOLE;3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE 97.0%;(3,5-dimethylisoxazol-4-yl)methylamine;(3,5-dimethylisoxazol-4-yl)methylamine hydrochloride;3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE;(diMethyl-1,2-oxazol-4-yl)MethanaMine;(3,5-Dimethylisoxazol-4-yl)methylamine, 4-(Aminomethyl)-3,5-dimethyl-1,2-oxazole;1-(3,5-Dimethylisoxazol-4-yl)methanamine hydrochloride | | CAS: | 131052-47-6 | | MF: | C6H10N2O | | MW: | 126.16 | | EINECS: | | | Product Categories: | Oxazoles, Isoxazoles & Benzoxazoles;Aminomethyl's;Oxazoles, Isoxazoles & Benzoxazoles;Oxazole&Isoxazole | | Mol File: | 131052-47-6.mol |  |
| | 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE Chemical Properties |
| Boiling point | 239.9±35.0 °C(Predicted) | | density | 1.069±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | crystalline powder | | pka | 8.30±0.29(Predicted) | | color | Colourless | | InChI | 1S/C6H10N2O.ClH/c1-4-6(3-7)5(2)9-8-4;/h3,7H2,1-2H3;1H | | InChIKey | WDDUIFIYJWSIOY-UHFFFAOYSA-N | | SMILES | NCC1=C(C)ON=C1C.[H]Cl |
| Hazard Codes | Xn | | Risk Statements | 22 | | HazardClass | IRRITANT | | HS Code | 2934999090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE Usage And Synthesis |
| Synthesis | General procedure for the synthesis of (3,5-dimethylisoxazol-4-yl)methanamine from 4-(chloromethyl)-3,5-dimethylisoxazole: To a solution of 4-(chloromethyl)-3,5-dimethylisoxazole (1.0 g, 6.9 mmol) in dioxane (10 mL) was added ammonia (10 mL). After the reaction mixture was stirred at room temperature for 16 h, it was concentrated and washed with acetonitrile (20 mL) to afford (3,5-dimethylisoxazol-4-yl)methanamine (800 mg, yield: 92%) as a white solid.1H NMR (400 MHz, DMSO-d6): δ= 8.52 (brs, 2H), 3.81 (s, 2H), 2.45 (s , 3H), 2.30 (s, 3H). | | References | [1] Patent: WO2018/132372, 2018, A1. Location in patent: Paragraph 00373
[2] Patent: US5089499, 1992, A |
| | 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE Preparation Products And Raw materials |
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