N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

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N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine manufacturers
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Basic information
Product Name:N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
Synonyms:IMatinib IMpurity C;N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 4-Methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline;Imatinib Imp.C;Imatinib Impurity 20;Imatinib EP Impurity F;N-(5-Amino-o-tolyl)-4-(3-pyridyl)-2-pyrimidinamine 4-Methyl-N3-[4-(3-pyridyl)-2-pyrimidinyl]-1,3-phenylenediamine;(5,AMINO 2-MethylPHENYL) 4,(3,PYRIDYL) 2,PYRIMIDINEAMINE;4-Methyl-N'-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
CAS:152460-10-1
MF:C16H15N5
MW:277.32
EINECS:442-110-5
Product Categories:Heterocycle-Pyrimidine series;intermidiate of Imatinib Methanesulfonate;Intermediate of Imatinib;Aromatics Compounds;Aromatics;Bases & Related Reagents;Inhibitors;Nucleotides;Imatinib
Mol File:152460-10-1.mol
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Structure
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Chemical Properties
Melting point 133-1350C
Boiling point 537.3±60.0 °C(Predicted)
density 1.266±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka4.77±0.10(Predicted)
color Yellow to Dark Yellow
InChIInChI=1S/C16H15N5/c1-11-4-5-13(17)9-15(11)21-16-19-8-6-14(20-16)12-3-2-7-18-10-12/h2-10H,17H2,1H3,(H,19,20,21)
InChIKeyQGAIPGVQJVGBIA-UHFFFAOYSA-N
SMILESC1(N)=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1
LogP1.68
CAS DataBase Reference152460-10-1(CAS DataBase Reference)
Safety Information
HS Code 29335990
MSDS Information
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Usage And Synthesis
Chemical PropertiesYellow Solid
UsesAbacavir intermediate
UsesN-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine (Imatinib EP Impurity F) is a selective inhibitor of protein kinase C (PKC). It is a COVID19-related research product.
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine Preparation Products And Raw materials
Preparation ProductsImatinib
Tag:N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine(152460-10-1) Related Product Information
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