| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:Thalidomide-PEG4-NH2 hydrochloride
CAS:2387510-82-7
Purity:>=95%(HPLC) Package:50mg Remarks:S57264
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| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
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| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:Thalidomide-O-PEG3-amine hydrochloride
CAS:2387510-82-7
Purity:99% HPLC Package:10MG;25MG;50MG;100MG;1G;5G
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Thalidomide-O-PEG3-amine HCl manufacturers
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| | Thalidomide-O-PEG3-amine HCl Basic information |
| Product Name: | Thalidomide-O-PEG3-amine HCl | | Synonyms: | Thalidomide-O-PEG3-amine HCl;Thalidomide-PEG4-NH2 (hydrochloride);Thalidomide-O-PEG3-amine hydrochloride;4-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;Thalidomide-PEG4-NH2, HCl salt;1H-Isoindole-1,3(2H)-dione, 4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1);Thalidomide 4'-ether-PEG3-amine;4-(H2N-PEG4)-Thalidomide HCl | | CAS: | 2387510-82-7 | | MF: | | | MW: | 485.92 | | EINECS: | | | Product Categories: | | | Mol File: | 2387510-82-7.mol |  |
| | Thalidomide-O-PEG3-amine HCl Chemical Properties |
| form | Solid | | color | White to off-white |
| | Thalidomide-O-PEG3-amine HCl Usage And Synthesis |
| Uses | Thalidomide-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | | Biological Activity | Thalidomide 4'-ether-PEG3-amine is a functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11 | | IC 50 | Cereblon | | storage | Store at -20°C | | References | [1] Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.[Content Brief] DOI:10.1038/nature13527 |
| | Thalidomide-O-PEG3-amine HCl Preparation Products And Raw materials |
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