6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)-

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6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)- Suppliers list
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
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6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)- Basic information
Product Name:6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)-
Synonyms:EEDi-5273 （APG-5918）;EEDi-5273;6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)-
CAS:2585648-55-9
MF:C26H22F4N6O2
MW:526.49
EINECS:
Product Categories:
Mol File:2585648-55-9.mol
6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)- Structure
6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)- Chemical Properties
density 1.55±0.1 g/cm3(Predicted)
pka1.42±0.20(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)- Usage And Synthesis
UsesEEDi-5273 is an exceptionally potent and orally efficacious EED inhibitor (IC50 = 0.2 nM) capable of achieving complete and persistent tumor regression.
References[1] Rej RK, et al. Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression. J Med Chem. 2021 Oct 14;64(19):14540-14556. DOI:10.1021/acs.jmedchem.1c01059
6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)- Preparation Products And Raw materials
Tag:6H-2,3a,5,7,11-Pentaazabenzo[4,5]cyclooct[1,2,3-cd]inden-6-one, 3-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-7,8-dihydro-7-(1-methylethyl)-10-(trifluoromethyl)-(2585648-55-9) Related Product Information
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