莫匹罗星钙(二水合物)
| 中文名称 | 莫匹罗星钙(二水合物) |
|---|---|
| 中文同义词 | 莫匹罗星钙;莫匹罗星钙(二水合物);莫匹罗星钙 USP标准品;莫匹罗星钙微粉;优选]MUPIROCIN CALCIUM HYDRATE;莫匹罗星钙|||MUPIROCIN CALCIUM;莫匹罗星钙,10 MM DMSO 溶液;莫匹罗星钙盐 |
| 英文名称 | MUPIROCIN CALCIUM, REFERENCE SPECTRUM EP STANDARD |
| 英文同义词 | MUPIROCIN CALCIUM, REFERENCE SPECTRUM EP STANDARD;Calcium mupirocin dihydrate;L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, calcium salt (2:1), dihydrate, [2E,8[2S,3S(1S,2S)]]- (9CI);mupirocin calcium hydrate;Calcium 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoate dihydrate;Mupirocin calcium dihydrate;Mupirocin Calcium (200 mg);5,9-ANHYDRO-2,3,4,8-TETRADEOXY-8-[[3-(2-HYDROXY-1-METHYLPROPYL)OXIRANYL]METHYL]-3-METHYL-[2E,8[2S,3S(1S,2S)]]-L-TALONONO |
| CAS号 | 115074-43-6 |
| 分子式 | C52H86CaO18.2H2O |
| 分子量 | 1075.34 |
| EINECS号 | 200-158-5 |
| 相关类别 | 医药原料 抗生素;其他化工产品;其他原料;医药原料;医药化工类;原料药;医药原料药-科研原料;其他原料;日用化学品;化学试剂;API |
| Mol文件 | 115074-43-6.mol |
| 结构式 |  |
莫匹罗星钙(二水合物) 性质
| 熔点 | 132-139 °C |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 极微溶于水，微溶于无水乙醇和二氯甲烷。 |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| 水溶解性 | Water: 6 mg/mL (5.58 mM) |
| InChIKey | DDHVILIIHBIMQU-UGPPHRKUNA-L |
莫匹罗星钙(二水合物)主要用作抗生素类医药原料。莫匹罗星钙(二水合物)主要成分是莫匹罗星钙，为莫匹罗星钙的二水合物形式。莫匹罗星是一种抗菌药物，用于治疗由金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌（MRSA）引起的皮肤感染，例如脓疱疮。它具有抗菌、抑制蛋白质合成和抗感染的双重作用。Mupirocin Calcium (Pseudomonic acid A)是mupirocin的钙盐形式。Mupirocin是一种天然的巴豆酸衍生物，提取自荧光假单胞菌，抑制细菌蛋白质合成，被用作一种抗生素。
Mupirocin Calcium Salt shows a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria. Mupirocin Calcium Salt is highly bound (95% bound) to the protein of human serum, and activity was reduced 10- to 20-fold in the presence of human serum.
Mupirocin Calcium Salt is well absorbed after oral and parenteral administration but serum antibiotic concentrations were short-lived as a result of extensive degradation to the antibacterially inactive metabolite, monic acid A.
安全信息
| WGK Germany | 3 |
|---|---|
| 海关编码 | 2941906000 |
| 毒性 | mouse,LD50,intravenous,1638mg/kg (1638mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 27, Pg. 195, 1996. |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-N7068 | 莫匹罗星钙(二水合物) Mupirocin calcium hydrate | 115074-43-6 | 25 mg | 500元 |
| 2025/12/22 | HY-N7068 | 莫匹罗星钙(二水合物) Mupirocin calcium hydrate | 115074-43-6 | 10 mM * 1 mLin DMSO | 550元 |